Celiac disease: effects on bone mineralization

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منابع مشابه

[Celiac disease: effects on bone mineralization].

* Professora-adjunta de Pediatria, Universidade Federal de Pernambuco. Doutora em Pediatria, EPM/UNIFESP. Até recentemente, a doença celíaca (DC) era considerada rara; acreditava-se que ela afetava sobretudo as crianças, e que se manifestava clinicamente de forma exuberante e característica. Com o surgimento dos testes sorológicos específicos a partir de 1980, tornou-se possível a investigação ...

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Bone Mineralization in Celiac Disease

Evidence indicates a well-established relationship between low bone mineral density (BMD) and celiac disease (CD), but data on the pathogenesis of bone derangement in this setting are still inconclusive. In patients with symptomatic CD, low BMD appears to be directly related to the intestinal malabsorption. Adherence to a strict gluten-free diet (GFD) will reverse the histological changes in th...

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DSPP effects on in vivo bone mineralization.

Dentin sialophosphoprotein has been implicated in the mineralization process based on the defective dentin formation in Dspp null mice (Dspp-/-). Dspp is expressed at low levels in bone and Dspp-/- femurs assessed by quantitative micro-computed tomography (micro-CT) and Fourier transform infrared spectroscopic imaging (FTIRI) exhibit some mineral and matrix property differences from wildtype fe...

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Celiac Disease, Gluten-Free Diet, and Bone Mass Density

Background: Celiac disease (CD), as an autoimmune disease has initiated since ingestion of food containing gluten. Constant intolerance to gluten causes damages of the small intestinal mucosa. One reason of mal-absorption in children and infants is CD. Additionally, about 75% of newly identified patients with CD have low bone mineral density (BMD). Many factors have role in metabolic bone disea...

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Effects of glucocorticoids on growth and bone mineralization.

OBJECTIVE To review the various mechanisms of glucocorticoid action and the ability of these agents to induce osteoporosis and growth deficits. SOURCES A review of the scientific literature was conducted on the basis of a MEDLINE search using the keywords and descriptors "glucocorticoids," "bone mineralization," "growth," and "side effects" and limited to articles published in the last decade...

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ژورنال

عنوان ژورنال: Jornal de Pediatria

سال: 2003

ISSN: 0021-7557

DOI: 10.2223/jped.1040